University of Vermont Cancer Center Member Profile

    David Seward, MD, PhD

    Assistant Professor, Pathology and Laboratory Medicine-Research

    Full Member
    Cancer Cell (CC)
    Academic Interests
    Each year lung cancer kills more people in the United States than breast, colorectal and prostate cancers combined. Immunotherapies, including anti-PD-1 monoclonal antibodies, may reduce lung cancer morbidity and mortality, but science can’t yet accurately predict which patients will benefit. The goal of the Seward Lab is to delineate the molecular mechanisms linking STK11 loss with anti-PD-1 therapy resistance in KRAS-driven lung adenocarcinoma and exploit that knowledge to restore sensitivity to current therapies while working to identify new treatment strategies.

    Other Titles, Distinctions and Appointments
    The Elmer R. Huber Early Career Green and Gold Professor in Pathology and Laboratory Medicine