University of Vermont Cancer Center Member Profile

Nataniel Lester-Coll, MD
Network Chair, Radiation Oncology
Division Chief, Radiation Oncology
Associate Professor, Radiation Oncology
Associate Member
Population Sciences and Cancer Outcomes (PSCO)
Academic Interests
I serve as local Principal Investigator for five cooperative group trials as Principal Investigator of the Hybrid Arc Palliative Radiation Therapy (HART) investigator-initiated trial, a Phase II study designed to reduce treatment-related toxicity and improve patient experience by using patient-reported outcomes as the primary endpoint. Additionally, I conduct large-scale database research using NCDB, SEER-Medicare, and claims-based datasets to analyze treatment trends, cost-effectiveness, and disparities in cancer care. My work integrates Markov modeling and decision analysis to optimize resource allocation in oncology.
Authors: Nataniel H. Lester-Coll, Joan Skelly, Pamela M. Vacek, Brian L. Sprague
Journal: Journal of Thoracic Disease
Publication Date: July 2022
Summary: This research examines the utilization trends and associated costs of stereotactic body radiation therapy (SBRT) in patients with metastatic non-small cell lung cancer, providing insights into its adoption and economic impact.
Link: https://pubmed.ncbi.nlm.nih.gov/35928617/
Cost-effectiveness of Prostate Radiation Therapy for Men With Newly Diagnosed Low-Burden Metastatic Prostate Cancer
Authors: Nataniel H. Lester-Coll, Steven Ades, James B. Yu, Adam Atherly, H. James Wallace III, Brian L. Sprague
Journal: JAMA Network Open
Publication Date: January 4, 2021
Summary: This study evaluates the cost-effectiveness of adding prostate radiation therapy to androgen deprivation therapy in men with newly diagnosed low-burden metastatic prostate cancer, suggesting potential economic benefits.
Link: https://pubmed.ncbi.nlm.nih.gov/33439266/
Insurance Status Correlates with Access to Procedural Therapy for Patients with Early-Stage Hepatocellular Carcinoma: A Retrospective Cohort Study of the National Cancer Database
Authors: Benjamin Weaver, Steven Lidofsky, Geoffrey Scriver, Nataniel Lester-Coll
Journal: Journal of Vascular and Interventional Radiology
Publication Date: May 2023
Summary: This retrospective cohort study analyzes how insurance status influences access to procedural therapies in patients with early-stage hepatocellular carcinoma, highlighting disparities in treatment based on insurance coverage.
Link: https://pubmed.ncbi.nlm.nih.gov/36596321/
Other Titles, Distinctions and Appointments
Top Reviewer Award, International Journal of Radiation Oncology, Biology, Physics
I serve as local Principal Investigator for five cooperative group trials as Principal Investigator of the Hybrid Arc Palliative Radiation Therapy (HART) investigator-initiated trial, a Phase II study designed to reduce treatment-related toxicity and improve patient experience by using patient-reported outcomes as the primary endpoint. Additionally, I conduct large-scale database research using NCDB, SEER-Medicare, and claims-based datasets to analyze treatment trends, cost-effectiveness, and disparities in cancer care. My work integrates Markov modeling and decision analysis to optimize resource allocation in oncology.
Authors: Nataniel H. Lester-Coll, Joan Skelly, Pamela M. Vacek, Brian L. Sprague
Journal: Journal of Thoracic Disease
Publication Date: July 2022
Summary: This research examines the utilization trends and associated costs of stereotactic body radiation therapy (SBRT) in patients with metastatic non-small cell lung cancer, providing insights into its adoption and economic impact.
Link: https://pubmed.ncbi.nlm.nih.gov/35928617/
Cost-effectiveness of Prostate Radiation Therapy for Men With Newly Diagnosed Low-Burden Metastatic Prostate Cancer
Authors: Nataniel H. Lester-Coll, Steven Ades, James B. Yu, Adam Atherly, H. James Wallace III, Brian L. Sprague
Journal: JAMA Network Open
Publication Date: January 4, 2021
Summary: This study evaluates the cost-effectiveness of adding prostate radiation therapy to androgen deprivation therapy in men with newly diagnosed low-burden metastatic prostate cancer, suggesting potential economic benefits.
Link: https://pubmed.ncbi.nlm.nih.gov/33439266/
Insurance Status Correlates with Access to Procedural Therapy for Patients with Early-Stage Hepatocellular Carcinoma: A Retrospective Cohort Study of the National Cancer Database
Authors: Benjamin Weaver, Steven Lidofsky, Geoffrey Scriver, Nataniel Lester-Coll
Journal: Journal of Vascular and Interventional Radiology
Publication Date: May 2023
Summary: This retrospective cohort study analyzes how insurance status influences access to procedural therapies in patients with early-stage hepatocellular carcinoma, highlighting disparities in treatment based on insurance coverage.
Link: https://pubmed.ncbi.nlm.nih.gov/36596321/
Other Titles, Distinctions and Appointments
Top Reviewer Award, International Journal of Radiation Oncology, Biology, Physics
