University of Vermont Cancer Center Member Profile
Yvonne Janssen-Heininger, PhD
Program Co-Leader, Cancer Cell, UVM Cancer Center
Professor, Pathology and Laboratory Medicine-ResearchProfessor, Pathology and Laboratory Medicine-Research
Full Member
Cancer Cell (CC)
Academic Interests
Lung cancers survive in a hostile environment and have to change their metabolism to survive. This poses a liability that can be used to kill the tumor. My laboratory's research is focus on understanding the mechanisms that lung tumors deploy to cope with the oxidative stress. We are identifying small molecules that prevent tumor survival that can be used clinically alongside chemotherapy or immunotherapy to improve survival. Our laboratory takes advantage of live tumor specimens and uses so called organoid cultures or precision tumor slices to test our compounds to have the greatest impact.
Other Titles, Distinctions and Appointments
University of Vermont Distinguished Professor
Lung cancers survive in a hostile environment and have to change their metabolism to survive. This poses a liability that can be used to kill the tumor. My laboratory's research is focus on understanding the mechanisms that lung tumors deploy to cope with the oxidative stress. We are identifying small molecules that prevent tumor survival that can be used clinically alongside chemotherapy or immunotherapy to improve survival. Our laboratory takes advantage of live tumor specimens and uses so called organoid cultures or precision tumor slices to test our compounds to have the greatest impact.
Other Titles, Distinctions and Appointments
University of Vermont Distinguished Professor